Opana is the brand name for the medication oxymorphone hydrochloride. It is a potent opioid pain medication used to treat moderate to severe pain. Opana 10mg tablet is one of the dosage strengths available for this medication. In this article, we will discuss the content of Opana 10mg tablet in detail.
Chemical Composition: Opana 10mg tablet contains oxymorphone hydrochloride as its active ingredient. The chemical name of oxymorphone hydrochloride is 4,5α-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride. The molecular formula of oxymorphone hydrochloride is C17H19NO4.HCl, and its molecular weight is 337.8 g/mol.
Pharmacology: Oxymorphone hydrochloride is a potent mu-opioid receptor agonist. It binds to the mu-opioid receptors in the brain and spinal cord, leading to the inhibition of pain signals. It also has sedative and respiratory depressant effects, which can lead to the side effects of the medication.
Indications: Opana 10mg tablet is indicated for the relief of moderate to severe pain. It is typically used in patients who require around-the-clock pain relief for an extended period. Opana 10mg tablet is not intended for use on an as-needed basis.
Dosage and Administration: The recommended starting dose for Opana 10mg tablet is 5 mg every 4 to 6 hours as needed for pain. The dose may be increased gradually as tolerated to achieve adequate pain relief. The maximum recommended dose of Opana 10mg tablet is 20 mg every 4 to 6 hours. The tablet should be swallowed whole with water and should not be crushed or dissolved.
Contraindications: Opana 10mg tablet is contraindicated in patients with a known hypersensitivity to oxymorphone or any of the tablet’s inactive ingredients. It should also not be used in patients who are experiencing respiratory depression or who have a known or suspected gastrointestinal obstruction.
Warnings and Precautions: Opana 10mg tablet should be used with caution in patients with a history of substance abuse or addiction, as it can be habit-forming. The medication should also be used with caution in patients with impaired renal or hepatic function, as the drug may accumulate in these patients and lead to increased side effects. Patients should also be monitored for respiratory depression, which is a potential side effect of the medication.
Side Effects: The most common side effects of Opana 10mg tablet include nausea, vomiting, constipation, dizziness, and headache. The medication can also cause respiratory depression, which can be life-threatening in severe cases. Other potential side effects include sedation, confusion, and euphoria.
Drug Interactions: Opana 10mg tablet should not be used in conjunction with other opioids, sedatives, or tranquilizers, as this can lead to increased sedation and respiratory depression. The medication may also interact with other drugs that affect the central nervous system, such as benzodiazepines, antipsychotics, and antidepressants.
Overdose: An overdose of Opana 10mg tablet can be life-threatening and should be treated as a medical emergency. Symptoms of an overdose may include respiratory depression, extreme sedation, and loss of consciousness. If an overdose is suspected, medical attention should be sought immediately.
Conclusion: In summary, Opana 10mg tablet contains oxymorphone hydrochloride, a potent opioid pain medication that is indicated for the relief of moderate to severe pain. The medication works by binding
click here for more medicine